Immunophenotyping in multiple myeloma and related plasma cell disorders
نویسندگان
چکیده
منابع مشابه
Immunophenotyping of plasma cells in multiple myeloma.
Multiparametric immunophenotyping of multiple myeloma (MM) and other plasma cell (PC) dyscrasias represents an attractive approach not only for research purposes but also in clinical practice. Based on well-established antigenic patterns, discrimination between myelomatous and normal PCs can be easily achieved in various types of samples, and this can be particularly valuable for the differenti...
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Multiple myeloma (MM) is an incurable plasma cell malignancy of the bone marrow. MM has 3 components: diffuse marrow infiltration, focal bone lesions, and soft-tissue (extramedullary) disease. The hallmark biomarker in blood or urine is a monoclonal immunoglobulin, the monoclonal protein. Waldenstrom macroglobulinemia is a similar disease with secretion of IgM. Staging is classically performed ...
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In the present study, the red blood cell values whether serum or plasma was pipette was tested and found to be a used and whether the test was performed suitable viscometer for detection of the at room temperature or 37#{176} C. Based on hyperviscosity syndrome in multiple these observations, a rapid screening test myeloma and macroglobulinemia. Addifor the measurement of serum or plasma tional...
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Plasma cell leukemia is very rare condition characterized by malignant proliferation of plasma cells in blood and bone marrow, which is aggressive and has a short survival even with conventional treatment. This ominous entity may be primary, or develops secondarily during the course of multiple myeloma. A 53-year-old Brazilian woman with multiple myeloma is described with bone marrow evaluation...
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In a recent issue of Blood, Saeed et all reported about the prognostic significance of plasma cell acid phosphatase (PCAP) in a large number of patients with multiple myeloma, showing that a low PCAP score (< 130) at diagnosis might recognize a subgroup of myelomatous patients with poor prognosis. I believe that such findings are quite surprising in view of the previously published cumulative d...
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ژورنال
عنوان ژورنال: Best Practice & Research Clinical Haematology
سال: 2010
ISSN: 1521-6926
DOI: 10.1016/j.beha.2010.09.002